Copper sulfate is acidic, with a pH of 3.8 in a 5% aqueous solution and a dark blue crystalline color. Due to the binding of copper ions in copper sulfate with proteins to form chelates, causing protein denaturation and precipitation, as well as deactivating enzymes in parasites, it can kill parasites, especially protozoa with strong killing ability. Many fish ponds use copper sulfate solution for fishing, which has a convergence effect on fish tissue at low concentrations. And it is often used in combination with ferrous sulfate in a ratio of 5:2.
I have encountered many farmers before, and I have heard from others' experiences that when fishing, high doses of copper sulfate are used, resulting in adult fish poisoning and a large number of deaths. Therefore, the use of copper sulfate should pay special attention to the following aspects:
1、 Water temperature
For the use of copper sulfate, water temperature is the key to affecting the effect. The toxicity of copper ions is positively correlated with water temperature, and the higher the temperature, the stronger its toxicity. It is best not to exceed 300 grams per acre when used in summer. When the temperature is below 30 degrees Celsius, 500 grams per acre of water can be used.
2、 Hardness
Copper sulfate belongs to acidic drugs, so when water is alkaline or weakly alkaline, its efficacy will be weakened due to acid-base neutralization. When in hard water, the carbonate in the water can react with copper sulfate to form carbonate precipitates, which can also lose some of its efficacy. Therefore, in high alkaline water and high hardness water, the amount of copper sulfate should be increased.
3、 Overfertilization of water quality
In the past, many people believed that copper sulfate was acidic, and most water bodies with more organic matter also showed weak acidity, so they unilaterally believed that the amount of copper sulfate should be reduced. In fact, in water bodies with abundant organic matter, due to the ability of proteins and hydroxyl compounds to combine with copper sulfate to form copper complexes, their efficacy is actually reduced,
4、 Salinity
Water bodies with high salinity are rich in table salt and calcium chloride. Under the action of dietary supplements and calcium chloride, the efficacy of ketone sulfate will be weakened. So the use of copper sulfate in seawater needs to greatly increase.







